Aim and Scope

The Journal of Medicinal Chemistry and Therapeutics (JMCT) is an international, peer-reviewed, open-access journal dedicated to publishing high-quality scientific research in medicinal chemistry, drug discovery, computational drug development, pharmacology, pharmacokinetics, therapeutic research, and related pharmaceutical and biomedical sciences. The journal provides a multidisciplinary platform for researchers to disseminate innovative findings that contribute to the discovery, design, characterization, evaluation, and development of novel therapeutic agents.

JMCT aims to advance modern drug discovery and therapeutic development by promoting interdisciplinary research integrating medicinal chemistry, chemical and protein structure analysis, computational drug design, molecular modeling, pharmacology, toxicology, pharmacokinetics, natural and synthetic product research, and related pharmaceutical sciences. The journal particularly encourages studies that provide meaningful mechanistic, structural, computational, experimental, or translational insights into drug discovery and therapeutic development.

The journal welcomes original and impactful contributions from researchers, clinicians, academicians, pharmaceutical scientists, and industry professionals worldwide. Manuscripts are evaluated based on scientific quality, originality, methodological rigor, ethical compliance, clarity of presentation, and their potential contribution to advancing medicinal chemistry, drug discovery, and therapeutic science.

Research Areas

The Journal of Medicinal Chemistry and Therapeutics welcomes high-quality manuscripts from a broad range of disciplines related to medicinal chemistry, drug discovery, therapeutic development, pharmaceutical sciences, and biomedical research. The journal particularly encourages interdisciplinary studies integrating chemical, computational, biological, pharmacological, toxicological, and translational approaches.

Medicinal Chemistry & Drug Design Medicinal Chemistry Drug Design and Optimization Structure–Activity Relationships (SAR) Lead Identification and Optimization Small-Molecule Drug Discovery Pharmaceutical Chemistry Bioactive Molecules and Chemical Probes Natural and Synthetic Drug Candidates	Drug Discovery & Development Drug Discovery and Development Target Identification and Validation Therapeutic Targeting Drug–Target Interactions Drug Repurposing Natural Product-Based Drug Discovery Synthetic Drug Discovery Preclinical Drug Development
Computational Drug Discovery Computational Drug Design Molecular Docking Molecular Dynamics Simulation Virtual Screening Structure-Based Drug Design Ligand-Based Drug Design Pharmacophore Modeling QSAR and Molecular Modeling Artificial Intelligence in Drug Discovery Machine Learning for Drug Development	Pharmacology & Therapeutics Pharmacology Experimental Pharmacology Therapeutic Development Mechanism of Drug Action Drug–Receptor Interactions Drug Efficacy and Safety Pharmacological Evaluation Translational Therapeutics Targeted Therapeutic Strategies
Pharmacokinetics, ADMET & Toxicology Pharmacokinetics Pharmacodynamics ADME and ADMET Drug Metabolism Drug Transport and Distribution Bioavailability Drug–Drug Interactions Drug Safety Assessment Toxicology and Safety Pharmacology In Silico Toxicity Prediction	Chemical, Structural & Biological Research Organic and Synthetic Chemistry Chemical Biology Protein Structure and Function Protein–Ligand Interactions Structural Biology Relevant to Drug Discovery Biochemical Evaluation Cellular and Molecular Studies Enzyme Inhibition Studies Biomolecular Interactions
Experimental & Preclinical Research In Vitro Studies In Vivo Studies Ex Vivo Studies Preclinical Research Mechanistic Studies Animal Pharmacology Efficacy Evaluation Safety and Toxicity Evaluation	Emerging & Translational Therapeutics Precision Drug Discovery AI-Driven Drug Discovery Computer-Aided Drug Design Drug Delivery and Therapeutic Systems Biomarker-Driven Therapeutics Translational Drug Research Emerging Therapeutic Technologies Interdisciplinary Pharmaceutical Research

Article Types

The Journal of Medicinal Chemistry and Therapeutics welcomes a variety of scholarly contributions that advance scientific knowledge in medicinal chemistry, drug discovery, computational drug development, pharmacology, pharmacokinetics, therapeutics, and related pharmaceutical sciences. The journal considers the following article categories:

Out of Scope

Manuscripts that fall outside the scientific scope of the journal or fail to meet the journal's standards of originality, scientific rigor, methodological quality, and ethical compliance may be declined without external peer review. Examples include, but are not limited to:

Editorial Standards

All submitted manuscripts are evaluated according to internationally recognized standards of scientific publishing. Editorial decisions are based on originality, scientific quality, methodological rigor, ethical compliance, clarity of presentation, reproducibility, and relevance to the aims and scope of the journal.

The Journal of Medicinal Chemistry and Therapeutics is committed to maintaining transparency, editorial independence, research integrity, and fairness throughout the editorial and peer-review process. The journal encourages authors to follow appropriate reporting guidelines, provide sufficient methodological details to support reproducibility, and comply with recognized ethical standards for scientific and therapeutic research.