Exploring the Therapeutic Promise of Ampelocissus latifolia: A Short Review

Shamia Zaman  Tanny; Md. Masum  Shahriar; Chowdhury Lutfun Nahar  Metu; Sunita Kumari  Sutihar; Md. Nasimul Haque  Shipon; Md. Sakib Al Hasan

doi:10.71193/jmct.20250007

Authors

Shamia Zaman Tanny Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj 8100, Bangladesh. Author
Md. Masum Shahriar Department of Pharmacy, Jahangirnagar University, Savar, Dhaka, Bangladesh Author https://orcid.org/0000-0003-3202-1095
Chowdhury Lutfun Nahar Metu Department of Biochemistry and Molecular Biology, Gopalganj Science and Technology University, Gopalganj Author https://orcid.org/0000-0002-8690-1058
Sunita Kumari Sutihar Department of Biochemistry and Molecular Biology, Gopalganj Science and Technology University, Gopalganj Author
Md. Nasimul Haque Shipon Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj 8100, Bangladesh Author https://orcid.org/0009-0001-7693-303X
Md. Sakib Al Hasan Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj 8100, Bangladesh Author https://orcid.org/0009-0004-7560-4041

DOI:

https://doi.org/10.71193/jmct.20250007

Keywords:

Ampelocissus latifolia, Cytotoxicity, Herbal medicine, Inflammation, Literature review, Pharmacological activity

Abstract

Ampelocissus latifolia (Roxb) (A. latifolia) belongs to the Grape family and subfamily of Vitoideae, and it has several pharmacological activities. This study aims to review the future perspective of the pharmacological potentiality of A. latifolia due to its distinct chemical constituents and functions. In vitro and in vivo study data were compiled from reputable sources, including PubMed, Springer Link, Scopus, Web of Science, ScienceDirect, and Google Scholar. Studies have revealed that the extract of A. latifolia lowered inflammation by inhibiting prostaglandin (PGs) and kinin synthesis. It has also demonstrated antimicrobial activity by disrupting bacterial protein synthesis. Additionally, it has antioxidant properties of this plant by lowering the reactive oxygen species (ROS) formation in the DPPH assay and FRAP assay. However, several studies also suggest that it showed cytotoxicity, antiproliferative, and apoptotic activity. This review underscores that A. latifolia has pharmacological promise using different cell lines, cell assays, and animal models.

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Author Biographies

Shamia Zaman Tanny, Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj 8100, Bangladesh.

Shamia Zaman Tanny is a Lecturer in the Department of Pharmacy at Gopalganj Science and Technology University, Bangladesh. She completed her Bachelor’s degree in Pharmacy from Jahangirnagar University, Savar. Her research focuses on drug discovery from natural products and plant sources, with particular interest in the development of anticancer agents and neuroscience-related therapeutics. She is passionate about exploring the medicinal potential of bioactive compounds and aims to contribute to innovative solutions in the fields of neuropharmacology and cancer treatment.
Md. Sakib Al Hasan, Department of Pharmacy, Gopalganj Science and Technology University, Gopalganj 8100, Bangladesh

Md. Sakib Al Hasan is a B. Pharm. student in Pharmacy at GSTU, Gopalganj 8100, Bangladesh. He is also working as a Financial and Documentation Officer at BioLuster Research Center Ltd., Dhaka, Bangladesh. He is mainly interested in cancer, neurology, computational drug design, in silico studies, vaccine designing, and natural compounds.

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